Cytotoxicity of guanine-based degradation products contributes to the antiproliferative activity of guanine-rich oligonucleotides† †Electronic supplementary information (ESI) available: Experimental details and supplementary figures. See DOI: 10.1039/c4sc03949a

Cytotoxicity of guanine-based degradation products contributes to the antiproliferative activity of guanine-rich oligonucleotides.

Guanine-rich oligonucleotides (GROs) have attracted considerable attention as anticancer agents, because they exhibit cancer-selective antiproliferative activity and can form G-quadruplex structures with higher nuclease resistance and cellular uptake. Recently, a GRO, AS1411 has reached phase II clinical trials for acute myeloid leukemia and renal cell carcinoma. The antiproliferative activity ...

Copper carbenes alkylate guanine chemoselectively through a substrate directed reaction† †Electronic supplementary information (ESI) available: For complete experimental details and characterization data. See DOI: 10.1039/c6sc03502g Click here for additional data file.

A series of tetraazalene radical-bridged M2 (M = CrIII, MnII, FeII, CoII) complexes with strong magnetic exchange coupling† †Electronic supplementary information (ESI) available: Experimental details, UV/Vis/NIR spectra for 2–8, additional magnetic data for 4–8, crystallographic data, selected bond distances, and crystallographic information files (CIFs) for 1, 2·0.4THF, 3·2.5THF, 4·2.5THF, and 5·2.9MeCN (CCDC 1414648–1414652). For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c5sc02725j

Guanine–oligothiophene conjugates: liquid-crystalline properties, photoconductivities and ion-responsive emission of their nanoscale assemblies† †Electronic supplementary information (ESI) available: Experimental, gHMBC NMR spectrum, DSC traces, lattice analyses, WAXRD spectra, POM images, FTIR spectra and transient photocurrent curves. See DOI: 10.1039/c7sc03764c

Multiplexed DNA detection based on positional encoding/decoding with self-assembled DNA nanostructures† †Electronic supplementary information (ESI) available: Experimental details, additional DNA detection figures, and DNA sequence information. See DOI: 10.1039/c4sc02696a Click here for additional data file.